Population-specific Conclusions about Modic Endplate Changes

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منابع مشابه

Characteristics and natural course of vertebral endplate signal (Modic) changes in the Danish general population

BACKGROUND Vertebral endplate signal changes (VESC) are more common among patients with low back pain (LBP) and/or sciatica than in people who are not seeking care for back pain. The distribution and characteristics of VESC have been described in people from clinical and non-clinical populations. However, while the clinical course of VESC has been studied in patients, the natural course in the ...

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Vertebral endplate (modic) changes and the treatment of back pain using antibiotics

• Vertebral endplate changes/modic changes (MC) are the MRI-images of inflammatory vertebral endplate damage that are often related to general disc degeneration. • In patients with prolonged back pain, the prevalence of MC is 40%. • In individuals with MC, more than 90% will have back pain within 1 year. • MC often causes localized pain 24/7. • Nocturnal pain is the rule rather than the excepti...

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Modic (Endplate) Changes in the Lumbar Spine: a preliminary Report on Bone Microarchitecture and Remodeling

Modic et al. in 1988 first described characteristic MRI changes in the vertebral body bone marrow and endplates, adjacent to degenerating intervertebral (iv) discs. Depending on the changes in T1 and T2 MRI signals, three types of lesions were identified: Type I lesions (low T1 and high T2 signal) are thought to be clinically active, due to increased blood flow within the bone. Type II lesions ...

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Prevalence, Patterns, and Genetic Association Analysis of Modic Vertebral Endplate Changes

STUDY DESIGN A prospective genetic association study. PURPOSE The etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However, studies with a larger patient subset are lacking, and candidate genes involved in other disc degeneration phenotypes have not been evaluated. We studied the prevalence of MCs and genetic associat...

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Intervertebral disc and vertebral endplate subchondral changes associated with Modic 1 changes of the lumbar spine: a cross-sectional study

BACKGROUND Modic 1 changes are usually associated with degenerative disc disease (DDD). We aimed to compare Modic 1 changes with advanced degenerative disc disease (>50%-intervertebral space narrowing [IVSN]) to Modic 1 changes with less advanced lumbar degenerative disc disease (≤50%-IVSN). METHODS We conducted a cross-sectional study. The computerized MRI database from a French tertiary car...

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ژورنال

عنوان ژورنال: Radiology

سال: 2010

ISSN: 0033-8419,1527-1315

DOI: 10.1148/radiol.100147